Yes, NITYR contains the active ingredient nitisinone. NTBC is an abbreviation for nitisinone and the two terms mean the same thing.

Cycle Pharmaceuticals manufactures NITYR in the UK and Switzerland.

NITYR is stable at room temperature between 68°F and 77°F (20°C and 25°C), allowing for excursions between 59°F and 86°F (15°C and 30°C) until its expiry date, and so freeing your patients from having to refrigerate the medication. NITYR tablets are very small² (baby aspirin sized) and can be taken with or without food at any time of the day.

For younger patients or patients that can’t swallow tablets, NITYR can also be converted to a suspension and taken via an oral syringe or can be crushed and mixed with applesauce.

Yes, clinical trials have demonstrated NITYR is bioequivalent to Orfadin* capsules, which means that it has the same efficacy, safety and side effects, and may offer patients and their families greater convenience.¹

NITYR may offer patients greater convenience. NITYR tablets are very small² (baby aspirin sized), do not require refrigeration and can be taken with or without food.³

To enroll a patient in NITYR, download the enrollment form, print it, complete all the required fields and either fax the form to Cycle Vita at + 1 (888) 385-8482 or email it to hello@cyclevita.life.

NITYR is an option for the treatment of Hereditary Tyrosinemia Type 1 and may offer convenience for patients. NITYR tablets are very small², do not require refrigeration and can be taken with or without food.³

NITYR Tablets are very small² (baby aspirin sized) and can be swallowed by patients from around 3 years old. However, the ability of the patient to swallow the tablet should be established by their healthcare provider.

For those unable to swallow a tablet, NITYR can be converted to a suspension that can be administered via an oral syringe and stored for up to 24 hours at room temperature before use. If your patient can swallow soft food, NITYR Tablets can also be crushed and mixed with applesauce.

Yes, Cycle Vita is available to eligible patients**. The Cycle Vita team is available so your patients can gain advice and support with access to a pharmacist when they need help or have any questions. Home delivery and proactive refills are also provided, making this process more convenient for your patients as well. We also offer $0 co-pay for eligible** patients.

For more information please refer patients to www.cyclevita.life or call +1 (888) 360-8482.

As part of Cycle’s dedication to providing NITYR to patients in an accessible and affordable manner, we provide a $0 co-pay to eligible** commercially insured patients (up to $25,000 towards a prescription for NITYR per year). For more information, please contact Cycle Vita on 1-888-360-8482.

Cycle Vita can complete a full benefits investigation for your patients. Please complete the enrollment form and send it back to the Cycle Vita team. You and your patients will be informed of the results from the investigation to support your decision making. Enrollment forms can be faxed to +1 (888) 360-8482 or emailed to hello@cyclevita.life

Please contact the Cycle Vita team on +1 (888) 360-8482.

For appointments and patient materials in the US, please contact +1 (888) 360-8482. For information about NITYR availability in other countries outside of the US, please contact sales-distribution@cyclepharma.com